Búsqueda | Biblioteca Virtual en Salud

1.

Discovery of highly neutralizing human antibodies targeting Pseudomonas aeruginosa.

Simonis, Alexander; Kreer, Christoph; Albus, Alexandra; Rox, Katharina; Yuan, Biao; Holzmann, Dmitriy; Wilms, Joana A; Zuber, Sylvia; Kottege, Lisa; Winter, Sandra; Meyer, Meike; Schmitt, Kristin; Gruell, Henning; Theobald, Sebastian J; Hellmann, Anna-Maria; Meyer, Christina; Ercanoglu, Meryem Seda; Cramer, Nina; Munder, Antje; Hallek, Michael; Fätkenheuer, Gerd; Koch, Manuel; Seifert, Harald; Rietschel, Ernst; Marlovits, Thomas C; van Koningsbruggen-Rietschel, Silke; Klein, Florian; Rybniker, Jan.

Cell ; 186(23): 5098-5113.e19, 2023 11 09.

Artículo Inglés | MEDLINE | ID: mdl-37918395

2.

Longitudinal Isolation of Potent Near-Germline SARS-CoV-2-Neutralizing Antibodies from COVID-19 Patients.

Kreer, Christoph; Zehner, Matthias; Weber, Timm; Ercanoglu, Meryem S; Gieselmann, Lutz; Rohde, Cornelius; Halwe, Sandro; Korenkov, Michael; Schommers, Philipp; Vanshylla, Kanika; Di Cristanziano, Veronica; Janicki, Hanna; Brinker, Reinhild; Ashurov, Artem; Krähling, Verena; Kupke, Alexandra; Cohen-Dvashi, Hadas; Koch, Manuel; Eckert, Jan Mathis; Lederer, Simone; Pfeifer, Nico; Wolf, Timo; Vehreschild, Maria J G T; Wendtner, Clemens; Diskin, Ron; Gruell, Henning; Becker, Stephan; Klein, Florian.

Cell ; 182(4): 843-854.e12, 2020 08 20.

Artículo Inglés | MEDLINE | ID: mdl-32673567

3.

Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody.

Schommers, Philipp; Gruell, Henning; Abernathy, Morgan E; Tran, My-Kim; Dingens, Adam S; Gristick, Harry B; Barnes, Christopher O; Schoofs, Till; Schlotz, Maike; Vanshylla, Kanika; Kreer, Christoph; Weiland, Daniela; Holtick, Udo; Scheid, Christof; Valter, Markus M; van Gils, Marit J; Sanders, Rogier W; Vehreschild, Jörg J; Cornely, Oliver A; Lehmann, Clara; Fätkenheuer, Gerd; Seaman, Michael S; Bloom, Jesse D; Bjorkman, Pamela J; Klein, Florian.

Cell ; 180(3): 471-489.e22, 2020 02 06.

Artículo Inglés | MEDLINE | ID: mdl-32004464

4.

Somatic hypermutation introduces bystander mutations that prepare SARS-CoV-2 antibodies for emerging variants.

Korenkov, Michael; Zehner, Matthias; Cohen-Dvashi, Hadas; Borenstein-Katz, Aliza; Kottege, Lisa; Janicki, Hanna; Vanshylla, Kanika; Weber, Timm; Gruell, Henning; Koch, Manuel; Diskin, Ron; Kreer, Christoph; Klein, Florian.

Immunity ; 56(12): 2803-2815.e6, 2023 Dec 12.

Artículo Inglés | MEDLINE | ID: mdl-38035879

5.

Single-cell analysis of memory B cells from top neutralizers reveals multiple sites of vulnerability within HCMV Trimer and Pentamer.

Zehner, Matthias; Alt, Mira; Ashurov, Artem; Goldsmith, Jory A; Spies, Rebecca; Weiler, Nina; Lerma, Justin; Gieselmann, Lutz; Stöhr, Dagmar; Gruell, Henning; Schultz, Eric P; Kreer, Christoph; Schlachter, Linda; Janicki, Hanna; Laib Sampaio, Kerstin; Stegmann, Cora; Nemetchek, Michelle D; Dähling, Sabrina; Ullrich, Leon; Dittmer, Ulf; Witzke, Oliver; Koch, Manuel; Ryckman, Brent J; Lotfi, Ramin; McLellan, Jason S; Krawczyk, Adalbert; Sinzger, Christian; Klein, Florian.

Immunity ; 56(11): 2602-2620.e10, 2023 Nov 14.

Artículo Inglés | MEDLINE | ID: mdl-37967532

6.

Antibody-mediated neutralization of SARS-CoV-2.

Gruell, Henning; Vanshylla, Kanika; Weber, Timm; Barnes, Christopher O; Kreer, Christoph; Klein, Florian.

Immunity ; 55(6): 925-944, 2022 06 14.

Artículo Inglés | MEDLINE | ID: mdl-35623355

7.

Analysis of antibodies from HCV elite neutralizers identifies genetic determinants of broad neutralization.

Weber, Timm; Potthoff, Julian; Bizu, Sven; Labuhn, Maurice; Dold, Leona; Schoofs, Till; Horning, Marcel; Ercanoglu, Meryem S; Kreer, Christoph; Gieselmann, Lutz; Vanshylla, Kanika; Langhans, Bettina; Janicki, Hanna; Ströh, Luisa J; Knops, Elena; Nierhoff, Dirk; Spengler, Ulrich; Kaiser, Rolf; Bjorkman, Pamela J; Krey, Thomas; Bankwitz, Dorothea; Pfeifer, Nico; Pietschmann, Thomas; Flyak, Andrew I; Klein, Florian.

Immunity ; 55(2): 341-354.e7, 2022 02 08.

Artículo Inglés | MEDLINE | ID: mdl-34990590

8.

Longitudinal Isolation of Potent Near-Germline SARS-CoV-2-Neutralizing Antibodies from COVID-19 Patients.

Kreer, Christoph; Zehner, Matthias; Weber, Timm; Ercanoglu, Meryem S; Gieselmann, Lutz; Rohde, Cornelius; Halwe, Sandro; Korenkov, Michael; Schommers, Philipp; Vanshylla, Kanika; Di Cristanziano, Veronica; Janicki, Hanna; Brinker, Reinhild; Ashurov, Artem; Krähling, Verena; Kupke, Alexandra; Cohen-Dvashi, Hadas; Koch, Manuel; Eckert, Jan Mathis; Lederer, Simone; Pfeifer, Nico; Wolf, Timo; Vehreschild, Maria J G T; Wendtner, Clemens; Diskin, Ron; Gruell, Henning; Becker, Stephan; Klein, Florian.

Cell ; 182(6): 1663-1673, 2020 09 17.

Artículo Inglés | MEDLINE | ID: mdl-32946786

9.

HIV-1 integration landscape during latent and active infection.

Cohn, Lillian B; Silva, Israel T; Oliveira, Thiago Y; Rosales, Rafael A; Parrish, Erica H; Learn, Gerald H; Hahn, Beatrice H; Czartoski, Julie L; McElrath, M Juliana; Lehmann, Clara; Klein, Florian; Caskey, Marina; Walker, Bruce D; Siliciano, Janet D; Siliciano, Robert F; Jankovic, Mila; Nussenzweig, Michel C.

Cell ; 160(3): 420-32, 2015 Jan 29.

Artículo Inglés | MEDLINE | ID: mdl-25635456

10.

Antibody Teamwork against Ebola Virus Disease.

Zehner, Matthias; Klein, Florian.

Immunity ; 52(2): 217-219, 2020 02 18.

Artículo Inglés | MEDLINE | ID: mdl-32075725

11.

Broadly neutralizing anti-HIV-1 antibodies require Fc effector functions for in vivo activity.

Bournazos, Stylianos; Klein, Florian; Pietzsch, John; Seaman, Michael S; Nussenzweig, Michel C; Ravetch, Jeffrey V.

Cell ; 158(6): 1243-1253, 2014 Sep 11.

Artículo Inglés | MEDLINE | ID: mdl-25215485

12.

Structural insights on the role of antibodies in HIV-1 vaccine and therapy.

West, Anthony P; Scharf, Louise; Scheid, Johannes F; Klein, Florian; Bjorkman, Pamela J; Nussenzweig, Michel C.

Cell ; 156(4): 633-48, 2014 Feb 13.

Artículo Inglés | MEDLINE | ID: mdl-24529371

13.

Broadly neutralizing antibodies and viral inducers decrease rebound from HIV-1 latent reservoirs in humanized mice.

Halper-Stromberg, Ariel; Lu, Ching-Lan; Klein, Florian; Horwitz, Joshua A; Bournazos, Stylianos; Nogueira, Lilian; Eisenreich, Thomas R; Liu, Cassie; Gazumyan, Anna; Schaefer, Uwe; Furze, Rebecca C; Seaman, Michael S; Prinjha, Rab; Tarakhovsky, Alexander; Ravetch, Jeffrey V; Nussenzweig, Michel C.

Cell ; 158(5): 989-999, 2014 Aug 28.

Artículo Inglés | MEDLINE | ID: mdl-25131989

14.

Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope.

Schoofs, Till; Barnes, Christopher O; Suh-Toma, Nina; Golijanin, Jovana; Schommers, Philipp; Gruell, Henning; West, Anthony P; Bach, Franziska; Lee, Yu Erica; Nogueira, Lilian; Georgiev, Ivelin S; Bailer, Robert T; Czartoski, Julie; Mascola, John R; Seaman, Michael S; McElrath, M Juliana; Doria-Rose, Nicole A; Klein, Florian; Nussenzweig, Michel C; Bjorkman, Pamela J.

Immunity ; 50(6): 1513-1529.e9, 2019 06 18.

Artículo Inglés | MEDLINE | ID: mdl-31126879

15.

Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization.

Klein, Florian; Diskin, Ron; Scheid, Johannes F; Gaebler, Christian; Mouquet, Hugo; Georgiev, Ivelin S; Pancera, Marie; Zhou, Tongqing; Incesu, Reha-Baris; Fu, Brooks Zhongzheng; Gnanapragasam, Priyanthi N P; Oliveira, Thiago Y; Seaman, Michael S; Kwong, Peter D; Bjorkman, Pamela J; Nussenzweig, Michel C.

Cell ; 153(1): 126-38, 2013 Mar 28.

Artículo Inglés | MEDLINE | ID: mdl-23540694

16.

Semen enhances transmitted/founder HIV-1 infection and only marginally reduces antiviral activity of broadly neutralizing antibodies.

von Maltitz, Pascal; Wettstein, Lukas; Weil, Tatjana; Schommers, Philipp; Klein, Florian; Münch, Jan.

J Virol ; 98(4): e0119023, 2024 Apr 16.

Artículo Inglés | MEDLINE | ID: mdl-38501840

17.

Torque Teno Virus load is associated with CDC stage and CD4+ cell count in people living with HIV but unrelated to AIDS-defining events and Human Pegivirus load.

Esser, Pia L; Quintanares, Gibran H Rubio; Langhans, Bettina; Heger, Eva; Böhm, Michael; Jensen, Björn-Erik Ole; Esser, Stefan; Lübke, Nadine; Fätkenheuer, Gerd; Lengauer, Thomas; Klein, Florian; Oette, Mark; Rockstroh, Juergen K; Boesecke, Christoph; Di Cristanziano, Veronica; Kaiser, Rolf; Pirkl, Martin.

J Infect Dis ; 2024 Jan 17.

Artículo Inglés | MEDLINE | ID: mdl-38230877

18.

HIV-1 infection of CD4 T cells impairs antigen-specific B cell function.

Kaw, Sheetal; Ananth, Swetha; Tsopoulidis, Nikolaos; Morath, Katharina; Coban, Bahar M; Hohenberger, Ralph; Bulut, Olcay C; Klein, Florian; Stolp, Bettina; Fackler, Oliver T.

EMBO J ; 39(24): e105594, 2020 12 15.

Artículo Inglés | MEDLINE | ID: mdl-33146906

19.

SARS-CoV-2 targets neurons of 3D human brain organoids.

Ramani, Anand; Müller, Lisa; Ostermann, Philipp N; Gabriel, Elke; Abida-Islam, Pranty; Müller-Schiffmann, Andreas; Mariappan, Aruljothi; Goureau, Olivier; Gruell, Henning; Walker, Andreas; Andrée, Marcel; Hauka, Sandra; Houwaart, Torsten; Dilthey, Alexander; Wohlgemuth, Kai; Omran, Heymut; Klein, Florian; Wieczorek, Dagmar; Adams, Ortwin; Timm, Jörg; Korth, Carsten; Schaal, Heiner; Gopalakrishnan, Jay.

EMBO J ; 39(20): e106230, 2020 10 15.

Artículo Inglés | MEDLINE | ID: mdl-32876341

20.

Hybrid immunity to SARS-CoV-2 in patients with chronic lymphocytic leukemia.

Mellinghoff, Sibylle C; Robrecht, Sandra; Sprute, Rosanne; Mayer, Leonie; Weskamm, Leonie M; Dahlke, Christine; Gruell, Henning; Teipel, Finn; Schlößer, Hans A; Siepmann, Klara; Thelen, Martin; Fink, Anna-Maria; Fischer, Kirsten; Klein, Florian; Addo, Marylyn M; Kolovou, Androniki; Cornely, Oliver A; Eichhorst, Barbara; Hallek, Michael; Langerbeins, Petra.

Eur J Haematol ; 112(5): 788-793, 2024 May.

Artículo Inglés | MEDLINE | ID: mdl-38311570

Biblioteca Virtual en Salud

BVS - Literatura Cientifica y Técnica

Su selección (0)

Formato de exportación:

Exportar:

Discovery of highly neutralizing human antibodies targeting Pseudomonas aeruginosa.

Longitudinal Isolation of Potent Near-Germline SARS-CoV-2-Neutralizing Antibodies from COVID-19 Patients.

Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody.

Somatic hypermutation introduces bystander mutations that prepare SARS-CoV-2 antibodies for emerging variants.

Single-cell analysis of memory B cells from top neutralizers reveals multiple sites of vulnerability within HCMV Trimer and Pentamer.

Antibody-mediated neutralization of SARS-CoV-2.

Analysis of antibodies from HCV elite neutralizers identifies genetic determinants of broad neutralization.

Longitudinal Isolation of Potent Near-Germline SARS-CoV-2-Neutralizing Antibodies from COVID-19 Patients.

HIV-1 integration landscape during latent and active infection.

Antibody Teamwork against Ebola Virus Disease.

Broadly neutralizing anti-HIV-1 antibodies require Fc effector functions for in vivo activity.

Structural insights on the role of antibodies in HIV-1 vaccine and therapy.

Broadly neutralizing antibodies and viral inducers decrease rebound from HIV-1 latent reservoirs in humanized mice.

Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope.

Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization.

Semen enhances transmitted/founder HIV-1 infection and only marginally reduces antiviral activity of broadly neutralizing antibodies.

Torque Teno Virus load is associated with CDC stage and CD4+ cell count in people living with HIV but unrelated to AIDS-defining events and Human Pegivirus load.

HIV-1 infection of CD4 T cells impairs antigen-specific B cell function.

SARS-CoV-2 targets neurons of 3D human brain organoids.

Hybrid immunity to SARS-CoV-2 in patients with chronic lymphocytic leukemia.